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While initial attempts have achieved partial recapitulation of testicular cell interactions, these models have not yet demonstrated the capacity to support complete spermatogenesis from stem cells to mature sperm (144)

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All cited studies are conducted in rodent or in-vitro systems consistent with the molecule's RUO classification

Fischman were obtained from the Developmental Studies Hybridoma Bank developed under the auspices of the NICHD and maintained by The University of Iowa, Department of Biological Sciences, Iowa City, IA 52242, Iowa